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Method for assessing cardiac function using magnetic resonance imaging

S J Soldo1, L J Haywood, S L Norris

  • 1Department of Medicine, LAC+USC Medical Center, Los Angeles 90033, USA.

Biomedical Instrumentation & Technology
|July 1, 1996
PubMed
Summary
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This study presents a magnetic resonance imaging (MRI) method for assessing cardiac function by analyzing left ventricular (LV) short-axis images. The protocol accurately estimates key cardiac output parameters like ejection fraction.

Area of Science:

  • Cardiovascular imaging
  • Medical physics
  • Cardiac physiology

Background:

  • Assessing cardiac function is crucial for diagnosing and managing cardiovascular diseases.
  • Magnetic resonance imaging (MRI) offers non-invasive visualization of cardiac structures and function.
  • Standardized protocols are needed for accurate and reproducible cardiac function assessment using MRI.

Purpose of the Study:

  • To develop and validate a magnetic resonance imaging (MRI) protocol for assessing human left ventricular (LV) cardiac function.
  • To establish a method for acquiring and analyzing short-axis LV images to determine key hemodynamic parameters.
  • To provide accurate and clinically relevant estimates of cardiac function using MRI.

Main Methods:

  • Utilized sagittal and axial scout 1H MR images to define the LV long axis.

Related Experiment Videos

  • Generated parallel short-axis imaging planes from the LV base to apex.
  • Acquired cardiac images using a fast-field echo technique with 6 slices and 16-20 phases per RR interval.
  • Manually traced endocardial borders, calculated LV volumes using Simpson's rule, and plotted volumes over time.

    • Main Results:

    • Successfully calculated LV volumes throughout the cardiac cycle (75-80% completion).
    • Determined clinically significant indices of cardiac function: stroke volume, ejection fraction, and cardiac output.
    • Demonstrated the feasibility of obtaining accurate LV volume measurements from the acquired short-axis images.

    Conclusions:

    • The developed MRI protocol provides accurate and useful estimates of left ventricular (LV) function.
    • This method enables reliable assessment of key cardiac parameters, aiding in clinical diagnosis and management.
    • Short-axis MRI imaging is a valuable tool for non-invasive cardiac function evaluation.