Related Experiment Video
Updated: Oct 17, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
Published on: March 2, 2014
Modified varicella-like syndrome
1Division of General Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Abstract:
After incidental exposure to natural varicella, up to 18% of vaccinees reported a breakthrough infection known as modified varicella-like syndrome (MVLS) over up to 10 years of postvaccination follow-up, compared with natural varicella occurring in similarly aged unvaccinated children at the rate of 9% per year. Children with MVLS are frequently asymptomatic, and their disease is characterized by having fewer lesions, less fever, and lasting fewer days than natural varicella. When a case of MVLS occurs there are few secondary cases, suggesting that it is infrequently transmitted. Sequelae such as secondary bacterial infection, cerebellar ataxia, encephalitis, and pneumonia occur infrequently.
More Related Videos
Related Concept Videos
Smallpox
Chickenpox
Poliomyelitis
Cytomegalovirus Disease
Respiratory Syncytial Virus Disease
Genital Herpes

