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DNA immunization
1Dept of Neuropharmacology, Scripps Research Insitute, La Jolla, CA 92037, USA.
Trends in Microbiology
|August 1, 1996
Abstract:
Inoculation with plasmid DNA vectors encoding immunogenic proteins induces both humoral and cell-mediated immune responses, which often provide protective immunity. Although many questions regarding the mechanism, efficacy and safety of DNA immunization remain to be addressed, this approach may offer a safer and more cost-effective alternative to conventional vaccines.