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Typhoid perforation

S N Khosla

    The Journal of Tropical Medicine and Hygiene
    |April 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Enteric perforation, a complication of enteric fever, occurred in 11.1% of cases. This study details its clinical features, management, and outcomes, highlighting a high mortality rate.

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    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Surgical Pathology

    Background:

    • Enteric fever, a systemic infection, can lead to severe complications.
    • Enteric perforation is a critical manifestation requiring prompt medical and surgical attention.

    Purpose of the Study:

    • To describe the clinical features, presentation, and diagnostic parameters of enteric perforation.
    • To analyze prognostic factors and outcomes of enteric perforation.
    • To discuss management strategies for enteric perforation.

    Main Methods:

    • Retrospective analysis of 270 enteric fever cases over 5 years.
    • In-depth review of 30 identified cases of enteric perforation.
    • Evaluation of clinical data, diagnostic findings, and treatment outcomes.

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    Main Results:

    • Enteric perforation occurred in 30 out of 270 (11.1%) enteric fever cases.
    • A high mortality rate was observed, with 18 deaths (60%) and 12 survivors (40%).
    • Clinical features, presentation patterns, and prognostic indicators were documented.

    Conclusions:

    • Enteric perforation is a significant complication of enteric fever with a substantial mortality risk.
    • Effective management requires a thorough understanding of clinical presentation and prognostic factors.
    • Further research into optimizing treatment strategies is warranted.