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[Successful topical administration of cyclosporin A in pyoderma gangraenosum]
U Theissen1, T A Luger, T Schwarz
1Hautklinik, Westfälischen Wilhelms-Universität, Münster.
Abstract:
Therapy of pyoderma gangrenosum can be complicated by side effects of the various systemic therapies, including corticosteroids, azathioprin and cyclosporin A. In this paper we report on a 49-year-old patient presenting with recalcitrant pyoderma gangrenosum who was treated successfully by topical application of cyclosporin A. Cyclosporin A serum levels were always in the subtherapeutic range, and no side effects were observed.