Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Weaning from ventilatory support

M R Lessard1, L J Brochard

  • 1Intensive Care Unit, Hôpital de l'Enfant-Jésus, Québec, Canada.

Clinics in Chest Medicine
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Including sheath effects in the interpretation of planar retarding potential analyzer's low-energy ion data.

The Review of scientific instruments·2016
Same author

Anesthesia breathing circuits protected by the DAR Barrierbac S breathing filter have a low bacterial contamination rate.

Canadian journal of anaesthesia = Journal canadien d'anesthesie·2001
Same author

Another feature of TURP syndrome: hyperglycaemia and lactic acidosis caused by massive absorption of sorbitol.

British journal of anaesthesia·2001
Same author

Submental endotracheal intubation: an alternative to tracheotomy in patients with midfacial and panfacial fractures.

The Journal of trauma·2000
Same author

Alfentanil causes less postoperative nausea and vomiting than equipotent doses of fentanyl or sufentanil in outpatients.

Anesthesiology·1999
Same author

Esophageal and tracheal distortion by the Esophageal-Tracheal Combitube: a cadaver study.

Canadian journal of anaesthesia = Journal canadien d'anesthesie·1999

Weaning patients from mechanical ventilation can be challenging. The rapid shallow breathing index (f/VT ratio) aids in predicting readiness, but a comprehensive approach is crucial for successful liberation from mechanical breathing support.

Area of Science:

  • Critical Care Medicine
  • Pulmonology
  • Respiratory Physiology

Background:

  • Mechanical ventilation is essential for acute respiratory failure but prolonged use complicates patient recovery.
  • Weaning from mechanical ventilation is difficult for a significant patient subset, increasing resource utilization.
  • Predictive indices and understanding underlying pathophysiology are key to optimizing ventilator liberation.

Purpose of the Study:

  • To review current strategies and challenges in weaning patients from mechanical ventilation.
  • To highlight the role of predictive indices and multifactorial assessment in difficult weaning scenarios.
  • To discuss the influence of ventilatory management and future technological advancements on weaning outcomes.

Main Methods:

  • Review of existing literature on mechanical ventilation weaning criteria and methods.

Related Experiment Videos

  • Analysis of factors contributing to weaning failure, including respiratory mechanics and patient-specific conditions.
  • Discussion of traditional weaning techniques (T-piece, IMV, PSV) and emerging computer-assisted systems.
  • Main Results:

    • The f/VT ratio (rapid shallow breathing index) shows the best predictive power among current indices but is not solely sufficient.
    • Increased respiratory workload (elastic, resistive) and respiratory muscle pump failure are common causes of weaning difficulty.
    • Left ventricular dysfunction can also impede successful weaning from mechanical ventilation.

    Conclusions:

    • Successful weaning requires a systematic approach, considering respiratory demand, muscle capacity, and patient comorbidities.
    • Ventilatory management significantly influences weaning outcomes, especially in difficult-to-wean patients.
    • Future computer-assisted systems may offer improved management strategies for ventilator liberation.