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Does multifrequency bioelectrical impedance relate to body composition?
H Suzuki1, J D Rounds, D W Wilmore
1Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
The Journal of Surgical Research
|September 1, 1996
Summary
Multifrequency bioelectrical impedance analysis shows strong correlations with body composition in normal rats. Further studies are needed to assess its utility in altered body fluid states.
Area of Science:
- Physiology
- Biomedical Engineering
- Body Composition Analysis
Background:
- Accurate, non-invasive bedside body composition measurement is needed.
- Bioelectrical impedance analysis (BIA) measures body resistance to electrical currents.
- Multifrequency BIA may differentiate between extracellular and intracellular fluid compartments.
Purpose of the Study:
- To determine the correlation between multifrequency BIA measurements and body composition in rats.
- To assess the potential of BIA as a bedside technique for body composition assessment.
Main Methods:
- Multifrequency BIA (3-300 kHz) was performed on rats (150-400 g).
- Body composition (total body water, fat, sodium, potassium) was measured via carcass analysis.
- Extracellular water was determined using sodium bromide dilution.
Main Results:
- Resistance index demonstrated high correlations with all body compartments (r=0.879-0.996).
- Strong intercorrelations were observed among body compartments (r=0.971-0.999).
- A specific relationship between BIA signals and individual compartments was not identified due to high intercorrelation.
Conclusions:
- Resistance index correlates with body compartments in normal populations.
- The clinical utility of multifrequency BIA requires investigation in conditions with altered body fluid distribution.