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Related Experiment Videos

Observations on hand movements in Rett syndrome: a pilot study

M Elian1, N de M Rudolf

  • 1Department of Neurology & Neurophysiology, Central Middlesex Hospital, London, England.

Acta Neurologica Scandinavica
|September 1, 1996
PubMed
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Rett syndrome hand movements are often asymmetrical and not midline, challenging previous assumptions. These movements, along with erratic breathing, may serve as a communication method for affected girls.

Area of Science:

  • Neurology
  • Developmental Disorders
  • Genetics

Background:

  • Rett syndrome is characterized by stereotyped hand movements, often assumed to be symmetrical and midline.
  • These movements have been thought to impede purposeful hand use.
  • The relationship between hand movements and respiration in Rett syndrome has not been previously investigated.

Purpose of the Study:

  • To explore the characteristics of hand stereotypy in Rett syndrome.
  • To investigate the relationship between hand movements and respiration in girls with Rett syndrome.
  • To determine if hand movements prevent purposeful hand use.

Main Methods:

  • Telephone interviews were conducted with parents of 25 girls diagnosed with Rett syndrome and disorganized breathing.

Related Experiment Videos

  • Data on hand movement patterns and their relationship with respiration were collected.

    • Main Results:

    • Hand movements were asymmetrical in 44% of the girls studied.
    • Girls with unilateral hand movements utilized the same hand for purposeful tasks.
    • In 72% of girls, hand movement intensity correlated with respiratory patterns (directly or inversely).
    • Hand movements appeared to fluctuate with emotional or mental state changes.

    Conclusions:

    • Contrary to prior assumptions, hand stereotypy in nearly half of Rett syndrome cases is asymmetrical and non-midline.
    • Hand movements do not inherently prevent purposeful hand use in Rett syndrome.
    • Hand movements and erratic breathing may function as a communication system for individuals with Rett syndrome.