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Observations on hand movements in Rett syndrome: a pilot study
1Department of Neurology & Neurophysiology, Central Middlesex Hospital, London, England.
Acta Neurologica Scandinavica
|September 1, 1996
Summary
Rett syndrome hand movements are often asymmetrical and not midline, challenging previous assumptions. These movements, along with erratic breathing, may serve as a communication method for affected girls.
Area of Science:
- Neurology
- Developmental Disorders
- Genetics
Background:
- Rett syndrome is characterized by stereotyped hand movements, often assumed to be symmetrical and midline.
- These movements have been thought to impede purposeful hand use.
- The relationship between hand movements and respiration in Rett syndrome has not been previously investigated.
Purpose of the Study:
- To explore the characteristics of hand stereotypy in Rett syndrome.
- To investigate the relationship between hand movements and respiration in girls with Rett syndrome.
- To determine if hand movements prevent purposeful hand use.
Main Methods:
- Telephone interviews were conducted with parents of 25 girls diagnosed with Rett syndrome and disorganized breathing.
- Data on hand movement patterns and their relationship with respiration were collected.
Main Results:
- Hand movements were asymmetrical in 44% of the girls studied.
- Girls with unilateral hand movements utilized the same hand for purposeful tasks.
- In 72% of girls, hand movement intensity correlated with respiratory patterns (directly or inversely).
- Hand movements appeared to fluctuate with emotional or mental state changes.
Conclusions:
- Contrary to prior assumptions, hand stereotypy in nearly half of Rett syndrome cases is asymmetrical and non-midline.
- Hand movements do not inherently prevent purposeful hand use in Rett syndrome.
- Hand movements and erratic breathing may function as a communication system for individuals with Rett syndrome.
