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Certain biophysical properties of Ukrain
Y M Susak1, M V Kurik, O V Kravchenko
1Department of General Surgery, Ukrainian State Medical University, Kiev Institute of Physics, Ukraine.
Drugs Under Experimental and Clinical Research
|January 1, 1996
Summary
Ukrain demonstrated significant in vitro resistance to ultraviolet radiation across the entire UV spectrum. Specific absorption peaks at 210 and 230 nm were notable in colorectal patients treated with Ukrain.
Area of Science:
- Biochemistry
- Photobiology
- Oncology
Background:
- Colorectal cancer remains a significant global health challenge.
- Understanding the interaction of therapeutic agents with UV radiation is crucial for treatment efficacy.
- The drug Ukrain has been investigated for its therapeutic potential.
Purpose of the Study:
- To investigate the in vitro UV radiation resistance of Ukrain.
- To analyze the absorption spectrum of Ukrain in biological samples.
- To identify specific spectral characteristics relevant to patient plasma.
Main Methods:
- In vitro irradiation of Ukrain across the UV spectrum.
- Spectrophotometric analysis of Ukrain.
- Analysis of plasma samples from colorectal cancer patients administered Ukrain.
Main Results:
- Ukrain exhibited relative resistance to UV radiation across the entire UV range.
- Seven distinct peaks were observed in the absorption spectrum of Ukrain.
- Prominent absorption peaks at 210 nm and 230 nm were identified in the plasma of treated colorectal patients.
Conclusions:
- Ukrain possesses inherent resistance to UV radiation.
- The spectral properties of Ukrain, particularly peaks at 210 and 230 nm, are detectable in patient plasma.
- These findings contribute to understanding Ukrain's behavior in a biological context.