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Dieulafoy's disease

P Fockens1, G N Tytgat

  • 1Department of Gastroenterology-Hepatology, Academic Medical Center, University of Amsterdam, The Netherlands.

Gastrointestinal Endoscopy Clinics of North America
|October 1, 1996
PubMed
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Dieulafoy's disease, a cause of gastrointestinal bleeding, involves a prominent artery near the stomach lining. Diagnosis requires careful endoscopic examination, with endoscopic therapy achieving high success rates for bleeding control.

Area of Science:

  • Gastroenterology
  • Vascular Medicine
  • Endoscopy

Background:

  • Dieulafoy's disease is a significant cause of upper gastrointestinal bleeding.
  • It is characterized by a large caliber artery located submucosally, close to the gastric epithelium.
  • While most common in the stomach, it can occur throughout the gastrointestinal tract.

Purpose of the Study:

  • To review the diagnostic and therapeutic approaches for Dieulafoy's disease.
  • To highlight the role of endoscopy in identifying and managing this vascular anomaly.
  • To discuss the efficacy of endoscopic hemostasis and alternative treatments.

Main Methods:

  • Review of literature on Dieulafoy's disease.
  • Emphasis on endoscopic diagnostic techniques, including meticulous mucosal inspection.

Related Experiment Videos

  • Discussion of endoscopic hemostasis methods and surgical alternatives.

    • Main Results:

    • Endoscopy is the primary diagnostic tool, though multiple procedures may be needed.
    • Endoscopic therapy, including endoscopic sclerotherapy (ES), is effective in 80-90% of cases when performed by experts.
    • Surgical options like wedge resection or vascular ligation are reserved for treatment failures.

    Conclusions:

    • Dieulafoy's disease requires careful endoscopic evaluation for diagnosis.
    • Endoscopic interventions offer a high success rate for managing bleeding.
    • Advancements in diagnostic techniques are expected to increase future diagnoses.