Central and peripheral haemodynamic effects of angiotensin

In 10 normotensive subjects intravenous infusion of angiotensin was followed by a significant increase in the arterial pressure, total peripheral resistance, central venous pressure and by a marked reduction of the intravascular forearm volume and venous distensibility. Forearm circulation time was shortened. The cardiac index, heart rate, forearm vascular resistance and the forearm blood flow did not change significantly.