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Gastroschisis: 13 years' experience at RCH Melbourne
1Department of Neonatology, Royal Children's Hospital, Parkville, Victoria, Australia.
Journal of Paediatrics and Child Health
|December 1, 1995
Summary
Gastroschisis has a low mortality rate. However, infants with short gut or bowel atresia experience prolonged total parenteral nutrition (TPN) and hospitalization, indicating significant complications.
Area of Science:
- Pediatric Surgery
- Neonatal Care
Background:
- Gastroschisis is a congenital abdominal wall defect.
- Understanding outcomes and risk factors is crucial for improving infant care.
Purpose of the Study:
- To review recent experience with gastroschisis.
- Analyze factors influencing mortality, morbidity, and complications.
Main Methods:
- Retrospective review of 49 infant admissions over 13 years (1980-1993).
- Analysis of factors impacting total parenteral nutrition (TPN) duration, hospital stay, mortality, and sepsis.
Main Results:
- Low mortality (4%), with deaths associated with bowel atresia.
- Short gut/resection and bowel atresia significantly increased TPN duration and hospital stay.
- Central venous line use was a significant risk factor for systemic sepsis.
Conclusions:
- Gastroschisis generally has a favorable prognosis with low mortality.
- Infants with specific complications (short gut, bowel atresia) face prolonged TPN and hospitalization with increased morbidity.