Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Microscopic polyarteritis]

C de Ancos Aracil1, J L Rebollar Mesa

  • 1Servicio de Medicina Interna II, Hospital Universitario, San Carlos, Madrid.

Anales De Medicina Interna (Madrid, Spain : 1984)
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Hemodyalisis as therapy of choice in lactic acidosis associated with metformin].

Revista clinica espanola·2002
Same author

[Pneumoperitoneum in an 81-year old woman].

Revista clinica espanola·2002
Same author

[Endocarditis caused by Actinobacillus actinomycetemcomitans].

Anales de medicina interna (Madrid, Spain : 1984)·2000
Same author

[Ischemic colitis: a descriptive analysis in a Madrid hospital].

Revista clinica espanola·1999
Same author

[Tuberculosis as cause of death].

Revista clinica espanola·1998
Same author

[Acute respiratory failure in a 79-year-old male].

Revista clinica espanola·1997
Same journal

[Giant cell arteritis: and uncommon cause of chronic cough].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same journal

[Pneumonia and lumbar spondylodiscitis as complications of Staphylococcus aureus's bacteriemia].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same journal

[Review of eleven cases of erythema induratum at a second level hospital].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same journal

[Primary bacteremias caused by Pasteurella multocida].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same journal

[Primary pulmonary lymphoma: an infrequent cause of pulmonary mass].

Anales de medicina interna (Madrid, Spain : 1984)·2009
Same journal

[Drugs and serotonin syndrome].

Anales de medicina interna (Madrid, Spain : 1984)·2009
See all related articles

Microscopic polyarteritis, a vasculitis, shares features with other conditions like Wegener granulomatosis, often presenting with rapidly progressive glomerulonephritis. Anti-neutrophil cytoplasmic antibodies aid in diagnosis and serologic marking of these vasculitides.

Area of Science:

  • Rheumatology
  • Nephrology
  • Immunology

Context:

  • Microscopic polyarteritis (MPA) is a systemic vasculitis characterized by inflammation of small blood vessels.
  • MPA shares clinical features with other small vessel vasculitides, notably Wegener granulomatosis (WG).
  • A common manifestation across this vasculitis group is rapidly progressive glomerulonephritis (RPGN).

Purpose:

  • To clarify the differential diagnosis of microscopic polyarteritis, which remains challenging.
  • To highlight the role of anti-neutrophil cytoplasmic antibodies (ANCA) in diagnosing and classifying these conditions.
  • To review the diagnostic utility of specific ANCA subtypes, such as antimyeloperoxidase (p-ANCA) in MPA and antiproteinase-3 (c-ANCA) in WG.

Summary:

  • Microscopic polyarteritis and Wegener granulomatosis are distinct vasculitides with overlapping clinical presentations, including RPGN.

Related Experiment Videos

  • Anti-neutrophil cytoplasmic antibodies (ANCA) are crucial serologic markers, with p-ANCA associated with MPA and c-ANCA with WG.
  • Despite diagnostic challenges, the similar therapeutic approaches for this group of vasculitides mitigate the impact of diagnostic ambiguity.

    • Impact:

    • Improved understanding of ANCA's role in differentiating vasculitides.
    • Provides a framework for managing patients with suspected microscopic polyarteritis.
    • Emphasizes the clinical relevance of serologic markers in systemic vasculitis management.