Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Three-dimensional structure of cell adhesion molecules

E Y Jones1

  • 1Laboratory of Molecular Biophysics, Oxford Centre for Molecular Sciences, The Rex Richards Building, South Parks Road, Oxford OX1 3QU, UK. Yvon@biop.ox.ac.uk.

Current Opinion in Cell Biology
|October 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.

Vitamins and hormones·2009
Same author

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.

Acta crystallographica. Section D, Biological crystallography·2006
Same author

Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2004
Same author

HLA-B27 and disease pathogenesis: new structural and functional insights.

Expert reviews in molecular medicine·2003
Same author

The human low affinity Fcgamma receptors IIa, IIb, and III bind IgG with fast kinetics and distinct thermodynamic properties.

The Journal of biological chemistry·2001
Same author

Gene polymorphism in Netherton and common atopic disease.

Nature genetics·2001
Same journal

Mechanosensing in immune cells: Implications for migration and beyond.

Current opinion in cell biology·2026
Same journal

Emerging role of organelles in cell migration.

Current opinion in cell biology·2026
Same journal

Nuclear adaptation in cell migration.

Current opinion in cell biology·2026
Same journal

Patterns in motion: Choreographing dynamic cell behaviours during tissue repair.

Current opinion in cell biology·2026
Same journal

Quo vadis reconstituted cell surfaces? Purpose and future perspectives for minimal systems of the cell plasma membrane.

Current opinion in cell biology·2026
Same journal

Nuclear determinants of mRNA and protein isoforms.

Current opinion in cell biology·2026
See all related articles

Structural data reveal key insights into cell adhesion, particularly cadherin-cadherin and integrin-ligand interactions. Understanding these protein-protein and protein-glycoconjugate recognition events is crucial for cell biology.

Area of Science:

  • Biochemistry
  • Structural Biology
  • Cell Biology

Background:

  • Cell adhesion is fundamental to multicellular organisms.
  • Specific interactions mediate cell-cell and cell-matrix recognition.
  • Structural insights are vital for understanding adhesion mechanisms.

Purpose of the Study:

  • To summarize recent advances in the structural characterization of cell adhesion.
  • To highlight key protein-protein and protein-glycoconjugate recognition events.
  • To provide insights into cadherin-cadherin and integrin-ligand mediated adhesion.

Main Methods:

  • Analysis of recent structural data.
  • Focus on high-resolution structural characterization techniques.
  • Integration of findings from various studies on cell adhesion molecules.

Related Experiment Videos

Main Results:

  • Detailed structural insights into cadherin-cadherin interactions.
  • Elucidation of the structural basis for integrin-ligand recognition.
  • Understanding of protein-glycoconjugate roles in cell adhesion.

Conclusions:

  • Recent structural data have significantly advanced our understanding of cell adhesion.
  • Structural characterization is key to deciphering the molecular mechanisms of adhesion.
  • These findings have implications for cell biology and potentially therapeutic interventions.