Distribution of oestradiol receptor molecules in human kidney

Experiments were performed to determine the distribution of oestrogen receptors in normal human kidney. Cytosols prepared from renal medulla and cortex were separately analyzed for oestrogen receptor molecules aga gel electrophoresis. Oestrogen receptors could be demonstrated in both compartments of the organ. However, the experiments reveal that the medulla is the main locus of oestrogen receptor in human kidney.