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Diphenhydramine overdose during pregnancy: lessons from the past
B C Brost1, J A Scardo, R B Newman
1Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425, USA.
American Journal of Obstetrics and Gynecology
|November 1, 1996
Abstract:
A primigravid woman was seen for the first time in a disoriented and combative state, with regular, painful uterine contractions. Evaluation revealed a negative illicit drug screen, no evidence of preeclampsia, and a nonfocal neurologic examination. Further workup revealed urinary diphenhydramine levels suggesting drug overdose. This case serves as a reminder of the oxytocin-like effects of diphenhydramine.