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A single pulsatile pump for total biventricular cardiac support using patient lung ventilation
1Biomedical Engineering Program, University of Texas at Austin, TX 78712, USA.
Summary
A novel extracorporeal pulsatile heart pump provides automatic biventricular cardiac support. This innovative device ensures volume balance between heart ventricles, crucial for advanced circulatory support systems.
Area of Science:
- Biomedical Engineering
- Cardiovascular Physiology
Background:
- Biventricular heart failure necessitates advanced circulatory support.
- Current devices often struggle with automatic inter-ventricular volume regulation.
Purpose of the Study:
- To develop and assess a modified extracorporeal pulsatile heart pump for biventricular cardiac support.
- To achieve automatic volume balance between the left and right ventricles.
Main Methods:
- Modification of an extracorporeal pulsatile heart pump with two independent fluid circuits.
- Utilizing a common pusher plate for simultaneous compression of both circuits.
- In vivo studies in pigs and in vitro testing for performance evaluation.
Main Results:
- Demonstrated feasibility in porcine models with physiologic flow during induced ventricular fibrillation.
- Achieved automatic beat-to-beat volume balance without external sensors.
- In vitro testing yielded outputs up to 7.0 L/min per circuit for adult human requirements.
Conclusions:
- The modified pulsatile heart pump effectively provides biventricular cardiac support.
- The device's automatic volume balancing mechanism is a significant advancement.
- This technology holds promise for treating advanced biventricular heart failure.