Related Experiment Video
Updated: Aug 4, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Cardiologic aspects of aortic valve surgery--who? when? what?
1Department of Cardiology, University of the Witwatersrand, Johannesburg, South Africa.
Insights
Surgical timing for aortic valve disease can be delayed in asymptomatic patients with congenital aortic stenosis. Left ventricular dysfunction improves after surgery for aortic stenosis, but chronic aortic regurgitation may indicate higher risks.
Area of Science:
- Cardiology
- Cardiac Surgery
- Valvular Heart Disease
Background:
- Aortic valve disease management involves complex decisions regarding surgical intervention timing and procedure choice.
- Conflicting literature and varied surgical approaches necessitate a review based on clinical experience.
Purpose of the Study:
- To discuss optimal surgical management strategies for aortic valve disease, focusing on timing and procedure selection.
- To provide insights into patient selection, surgical risks, and long-term outcomes based on clinical expertise.
Main Methods:
- Clinical experience of a cardiologist in managing patients with aortic valve disease.
- Review of patient factors including age, lesion severity, physical condition, and comorbidities.
- Analysis of surgical outcomes for aortic stenosis and aortic regurgitation.
Main Results:
- Delayed surgery is safe for hemodynamically significant congenital aortic stenosis in asymptomatic young patients with normal stress tests.
- Left ventricular dysfunction in severe aortic stenosis consistently improves postoperatively, supporting surgical intervention.
- Chronic severe aortic regurgitation with specific indicators (e.g., low ejection fraction, cardiomegaly) suggests higher operative mortality but not absolute contraindication.
Conclusions:
- Symptomatic patients with severe aortic stenosis have no cardiac contraindication to surgery, as myocardial function improves postoperatively.
- While certain factors increase risk in chronic aortic regurgitation, they do not justify deferring surgery.
- Significant variability exists in surgical approach selection for aortic valve disease, highlighting a need for greater standardization and research.
Abstract:
The title invites a discussion of a patient (age, lesion, physical condition, compliance, and other organ pathology) with aortic valve disease in the context of proposed surgical management. It further seeks clarification on the timing of such surgical contribution and on which operation is optimal. Without reviewing all the vast and somewhat conflicting literature, these aspects are addressed by a clinical cardiologist based principally on his own experience. Among the principal conclusions are the following: a) Surgery can safely be delayed in hemodynamically significant congenital aortic stenosis in children or young adults provided that the patients are nearly asymptomatic and that submaximal or maximal stress testing shows minimal or no ST-T changes. b) Prognosis after successful valve surgery for critically tight aortic stenosis in middle-aged and elderly patients differs from that for aortic regurgitation in that left ventricular myocardial dysfunction, however severe, will always improve postoperatively in the former condition. There is, therefore, never a cardiac contraindication to surgical management of symptomatic patients with tight aortic stenosis. c) Certain features in cases of chronic severe aortic regurgitation, such as diminished ejection fraction, increased end-systolic left ventricular diameter, electrocardiographic repolarization abnormalities, marked cardiomegaly on radiologic examination, and NYHA class III or IV symptoms, reflect a higher operative mortality and poorer long-term prognosis. Nevertheless, none of these features, alone or combined, can to date justify a definite contraindication to surgery in a specific patient. d) There is little uniformity or agreement among surgeons, including their cardiologists if or when that is pertinent, on the type of operation for patients of any age requiring aortic valve surgery. For example, a patient aged 40 years and depending on the "whims and fancies" of a Department or indeed those of an individual surgeon, which include his own judgement of his technical ability, may be subjected to a repair, a Ross procedure, insertion of a homograft or replacement with one of a variety of bioprosthetic and mechanical valves. The reasons, logic or motives behind these different choices are sometimes difficult, certainly for this author, to comprehend. Hopefully, ongoing international experience and research endeavors will, at least partially, clarify the current confusion. There is presumably an "optimal" way to hold a golf club or to kick a football?! The skill and judgement of the operators will, inevitably and sometimes regrettably, always vary.
More Related Videos
Related Concept Videos
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management
Aortic Regurgitation IV: Nursing Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Aneurysm IV: Nursing Management

