Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small aortic root in neonates

C Frescura1, G Thiene

  • 1Institute of Pathological Anatomy, University of Padua Medical School, Italy.

The Journal of Heart Valve Disease
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Successful use of sirolimus in a patient with cardiac microangiopathy in primary antiphospholipid syndrome.

Scandinavian journal of rheumatology·2019
Same author

Letter to the Editor.

Journal of veterinary internal medicine·2017
Same author

Naturally Occurring Biventricular Noncompaction in an Adult Domestic Cat.

Journal of veterinary internal medicine·2017
Same author

Autopsy after transcatheter aortic valve implantation.

Virchows Archiv : an international journal of pathology·2017
Same author

Sudden cardiac arrest in sports - need for uniform registration: A Position Paper from the Sport Cardiology Section of the European Association for Cardiovascular Prevention and Rehabilitation.

European journal of preventive cardiology·2015
Same author

Arrhythmogenic right ventricular cardiomyopathy. Contribution of cardiac magnetic resonance imaging to the diagnosis.

Herz·2015
Same journal

Impact of Patient-Specific Material Properties on Aneurysm Wall Stress: Finite Element Study.

The Journal of heart valve disease·2021
Same journal

Range of Pulmonary Autograft Responses to Systemic Pressure Immediately After Ross Procedure.

The Journal of heart valve disease·2021
Same journal

Evolution of Bilateral Mammary Arterial Grafting Program in Veterans Affairs Medical Center.

The Journal of heart valve disease·2021
Same journal

Double Valve Failure Due to Perceval Sutureless Aortic Valve Migration.

The Journal of heart valve disease·2018
Same journal

Use of AngioVac for Removal of Tricuspid Valve Vegetation.

The Journal of heart valve disease·2018
Same journal

Management of Late Paravalvular Leak after Transcatheter Valve Placement in Calcified Mitral Annulus.

The Journal of heart valve disease·2018
See all related articles

Neonatal aortic stenosis often results from a unicommissural aortic valve, characterized by a single leaflet and abnormal structure. This congenital heart defect typically prevents biventricular repair due to associated cardiac anomalies.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease
  • Cardiac Surgery

Background:

  • Small aortic root in neonates and infants is frequently linked to unicommissural aortic valve, a condition with a single leaflet and an eccentrically positioned commissure.
  • This anatomical variation inherently leads to aortic stenosis due to a narrow aortic ring, a stenotic valve orifice, and leaflet abnormalities.

Purpose of the Study:

  • To elucidate the pathophysiology of aortic stenosis in neonates with unicommissural aortic valve.
  • To highlight the implications of associated cardiac anomalies on surgical repair strategies.

Main Methods:

  • Review of echocardiographic and surgical data from neonates diagnosed with unicommissural aortic valve.
  • Analysis of aortic root dimensions, valve morphology, and associated intracardiac and great vessel abnormalities.

Related Experiment Videos

Main Results:

  • Unicommissural aortic valve is a primary cause of aortic stenosis in affected infants.
  • Associated conditions such as hypoplastic left ventricle, endocardial fibroelastosis, mitral valve dysplasia, and aortic arch obstruction are common.
  • These complex anomalies frequently preclude the possibility of a biventricular repair.

Conclusions:

  • Unicommissural aortic valve represents a significant cause of congenital aortic stenosis in neonates.
  • The frequent co-occurrence of multiple cardiac defects complicates management and often necessitates alternative surgical approaches beyond biventricular repair.