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Some physico-chemical properties micelle--benzalkonium chloride (BAC) adduct on interface in selected eye drops
E Zawadzka1, P Stefański, M M Zgoda
1Department of Applied Pharmacy, Medical University of Lodz, Poland.
Acta Poloniae Pharmaceutica
|July 1, 1995
Abstract:
In selected eye drops the value of surface tension coefficient delta 25 and critical micelle concentration (cmc) was determined. Calculation of the hydrophilic-lipophilic balance level (HLBcmc) and the solution of the surface state f.Am = K.T form of Gibbs equation enables the estimation of the type of action of micelle with lipid corneal epithelium. Particular attention has been paid to the forms of eye drops which contain benzalkonium chloride (BAC).