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[Changes in corneal topography after using tear substitutes]

C W Emde1, H Brewitt, R Winter

  • 1Augenklinik der Medizinischen Hochschule Hannover.

Klinische Monatsblatter Fur Augenheilkunde
|June 1, 1996
PubMed
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High-viscosity tear substitutes significantly alter corneal topography and astigmatism, unlike low-viscosity options. Avoid high-viscosity gels before keratometry in normal eyes to ensure accurate measurements.

Area of Science:

  • Ophthalmology
  • Optometry
  • Corneal Physiology

Background:

  • Computer-controlled video keratoscopy is increasingly utilized for diverse ophthalmic indications.
  • Understanding the impact of artificial tear formulations on corneal topography is crucial for accurate assessments.

Purpose of the Study:

  • To investigate the effects of high-viscosity and low-viscosity tear substitutes on corneal topography.
  • To compare the immediate and short-term changes induced by different tear substitute viscosities.

Main Methods:

  • Evaluated corneal topography in 14 normal eyes from 7 subjects.
  • Applied high-viscosity and low-viscosity tear substitutes, assessing changes at one and five minutes post-application.

Main Results:

Related Experiment Videos

  • High-viscosity preparations significantly increased astigmatism and altered the corneal axis shortly after application.
  • Low-viscosity preparations induced variations within the normal range of measurement variability.
  • The effects of high-viscosity preparations were more pronounced and persistent than those of low-viscosity ones.

Conclusions:

  • High-viscosity tear substitutes (gels) should not be used immediately before keratometry in normal eyes due to induced topographical changes.
  • These viscous preparations may be beneficial prior to contact lens fitting in post-keratoplasty patients.
  • Keratometry can aid in determining the in-vivo residence time of ophthalmic preparations based on their viscosity.