Methotrexate patient education: a quality improvement study

Area of Science:

• Rheumatology
• Patient Education
• Pharmacology

Background:

• Methotrexate (MTX) is a common medication in rheumatology.
• Patient understanding of MTX safe use and toxicity is crucial for adherence and safety.
• Educational interventions may improve patient knowledge regarding MTX therapy.

Purpose of the Study:

• To assess patient knowledge of methotrexate (MTX) safe use and toxicity.
• To evaluate the effectiveness of educational interventions by a rheumatology nurse in improving MTX understanding.
• To identify factors influencing patient knowledge of MTX therapy.

Main Methods:

• 183 patients receiving MTX completed an initial knowledge questionnaire.
• A rheumatology nurse provided education and reviewed correct answers.
• 138 patients completed a follow-up questionnaire to assess knowledge change.
• Knowledge scores were analyzed to determine improvements and influencing factors.

Main Results:

• Mean MTX knowledge scores significantly increased from 7.32 to 10.23 (P < 0.001).
• A supplemental MTX pocket-card was associated with higher follow-up scores (OR = 2.37, P = 0.021).
• Patients over 55 had significantly poorer knowledge scores compared to those under 45 (OR = 0.23, P = 0.013).

Conclusions:

• A rheumatology nurse-led education program effectively improved patient knowledge of MTX toxicity and safe use.
• Older patients (over 55) are at higher risk for knowledge deficits regarding MTX.
• A simple MTX pocket-card is a beneficial addition to patient education programs.