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Antiphospholipid syndrome presenting as episodic limb ischaemia
R E Evans1, M J Dillon, M Alfaham
1Department of Child Health, Llandough Hospital, South Glamorgan.
Archives of Disease in Childhood
|October 1, 1996
Insights
A pediatric patient experienced leg ischemia due to high anticardiolipin antibodies. Low-dose aspirin treatment resolved symptoms and normalized antibody levels, suggesting long-term use may be beneficial.
Area of Science:
- Pediatric Cardiology
- Immunology
Background:
- Antiphospholipid syndrome can manifest in children, presenting with thrombotic events.
- Ischemic episodes in infants require thorough investigation for underlying causes like autoimmune conditions.
Abstract:
A child presented with ischaemic episodes of his left leg from the age of 2 months. He was found to have raised anticardiolipin antibodies so was started on low dose aspirin. At a three year follow up he was asymptomatic with a normal anticardiolipin antibody level while taking aspirin daily, probably for life.