[Dynamics of immunoglobulins M and G formation in experimental tularemia]

There were revealed certain differences in the structure and the level of immunoglobulins, the time of their persistence in the blood of the infected and vaccinated experimental animals in tularemia. IgG were characteristic chiefly of the infectious process and served as an index of the immunological response intensity. Vaccination conditioned the production of IgM. IgG were revealed in low titres and at earlier periods of study. The results coincided in using cystein hidrochloride and 2-mercaptoethanol (reducing agents).