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Pharmacology of cancer chemotherapy in the older person
1Department of Pharmacology and Medicine, University of Texas Health Science Center, San Antonio, Texas, USA.
Clinics in Geriatric Medicine
|February 1, 1997
Abstract:
With more widespread use of effective chemotherapy, more elderly patients are candidates for treatment with cytotoxic drugs. This article reviews and discusses the relevant age-related factors that may alter drug disposition and its relationship to pharmacokinetics effects and to pharmacodynamic effects in the elderly.