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Acute hepatitis and drug-related lupus induced by minocycline treatment
P E Golstein1, J Deviere, M Cremer
1Department of Gastroenterology, Erasmus Hospital, Université Libre de Bruxelles, Belgium.
The American Journal of Gastroenterology
|January 1, 1997
Abstract:
Minocycline is widely prescribed for long-term treatment in acne. Major side effects are rare and include hepatitis and drug-related lupus. Hepatitis can be early and acute or late and chronic, whereas lupus presents as a tardive and insidious disease. We report a case of minocycline-induced lupus initially presenting as acute hepatitis, evolving to chronic cytolysis, in a young man treated for facial acne.