Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Embryonal metabolism]

C Khatchadourian1, C Joly, Y Ménézo

  • 1INSA Unité de Biologie du développement pré-implantatoire, UA INRA 203, Villeurbanne.

Contraception, Fertilite, Sexualite (1992)
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A parametric study assessing Implicit Solver limits for a generic FEM Simulation of PTA without stent deployment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2023
Same author

Balint's syndrome revealing Creutzfeldt-Jakob disease.

Revue neurologique·2021
Same author

[Importance of the determination of MTHFR SNPs (Methylene Tetrahydrofolate Reductase Single Nucleotide Polymorphisms) in couple infertility].

Gynecologie, obstetrique, fertilite & senologie·2020
Same author

Metabolic enhancers supporting 1-carbon cycle affect sperm functionality: an in vitro comparative study.

Scientific reports·2018
Same author

Increased pregnancy rate using standardized coculture on autologous endometrial cells and single blastocyst transfer : a multicentre randomized controlled trial.

Cellular and molecular biology (Noisy-le-Grand, France)·2016
Same author

[Not Available].

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2015
Same journal

[Inflammatory and/or locally advanced breast cancers. Difficulty evaluating the response to initial chemotherapy].

Contraception, fertilite, sexualite (1992)·2000
Same journal

[Proximal tubal unblocking by selective salpingography, apropos of 8 cases].

Contraception, fertilite, sexualite (1992)·2000
Same journal

[Anatomoclinical correlations of endometriosis].

Contraception, fertilite, sexualite (1992)·2000
Same journal

[Effects of raloxifene on bone loss and fracture risk in the menopausal woman].

Contraception, fertilite, sexualite (1992)·2000
Same journal

[Cytological screening of uterine cervical cancer by samples in liquid medium (CytoRich). Preliminary study of a series of 111 292 patients].

Contraception, fertilite, sexualite (1992)·2000
Same journal

[Diabetes before pregnancy, apropos of 143 cases].

Contraception, fertilite, sexualite (1992)·2000
See all related articles

Understanding embryo metabolism is complex and varies by species and developmental stage. Optimizing nutrient balance in culture media is crucial for preventing developmental issues.

Area of Science:

  • Developmental Biology
  • Metabolomics
  • Reproductive Science

Context:

  • Embryo metabolism understanding is challenging due to interspecies and stage-specific variations.
  • Basic compounds like glucose can be toxic at high concentrations but are metabolized by embryos at low levels.
  • High amino acid levels are detrimental due to ammonia release, though essential in moderation.

Purpose:

  • To elucidate the complexities of early embryo metabolism.
  • To identify optimal nutrient concentrations and balances for embryonic development.
  • To address challenges in in vitro culture media formulation.

Summary:

  • Embryo metabolism is highly variable, influenced by species and developmental stage (pre- and post-genomic activation).
  • Glucose is actively metabolized at low concentrations, but high levels can be toxic.

Related Experiment Videos

  • Amino acids are necessary but can cause developmental issues (ammonia toxicity) if concentrations are too high.
  • Addition of serum or biological fluids is generally not beneficial.
  • Further research into embryo metabolism is vital to prevent culture-related developmental delays or blocks.

    • Impact:

    • Provides insights into optimizing in vitro fertilization (IVF) culture media.
    • Aims to improve success rates in assisted reproductive technologies.
    • Highlights the need for stage-specific and species-specific nutrient formulations for better embryo development outcomes.