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CYP2E1 genotypes and serum LAP in Japanese alcoholics
R Miyatake1, H Suwaki, K Nakamura
1Department of Neuropsychiatry, Kagawa Medical School, Kita-gun, Japan.
Life Sciences
|February 17, 1995
Abstract:
The genotypes of the ALDH2 and CYP2E1 loci of Japanese alcoholic patients were determined to investigate the susceptibility to alcoholic liver injury. In alcoholics with a liver-function disorder, a significant association was observed between the genotypes of the CYP2E1 loci and the serum level of a liver-derived enzyme, LAP. However, there was no significant association between the ALDH2 genotypes and liver dysfunction.