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[The clinical analysis of pediatric meningioma: 5 cases]
Abstract:
Five cases of pediatric meningioma were reported with special emphasis on the clinical features. These cases consisted of three boys and two girls between eight and fifteen years old. Two were falx meningioma, two were suprasellar, and one was petroclival. One falx meningioma was associated with Neurofibromatosis II, and a suprasellar case had no dural attachment, but had cystic component after recurrence. Histologically, there were three meningothelial, one transitional, and one fibrous meningioma. No malignant meningioma was found among any of the cases. Two cases received postoperative irradiation and had no recurrence. A falx meningioma with Neurofibromatosis II and a suprasellar with no dural attachment had evidence of recurrence. The latter suffered from severe neurological deficits after reoperation. It was suggested that irradiation against residual tumor should be considered. However, total removal should be carried out in pediatric cases of meningioma. The authors concluded that our cases had features intermediate between adult meningiomas and pediatric meningiomas because the majority of cases were senior children.
Insights
Pediatric meningioma cases highlight clinical features and treatment outcomes. Complete surgical removal is crucial, with adjuvant irradiation considered for residual tumors to prevent recurrence.
Area of Science:
- Neuro-oncology
- Pediatric Neurosurgery
Background:
- Meningiomas are rare in children, presenting unique clinical and histological challenges.
- Understanding pediatric meningioma characteristics is vital for effective management.
Observation:
- Five pediatric meningioma cases (3 male, 2 female, ages 8-15) were analyzed.
- Tumor locations included falx, suprasellar, and petroclival regions.
- One case had Neurofibromatosis II; another suprasellar case lacked dural attachment and recurred.
Findings:
- Histological subtypes were meningothelial, transitional, and fibrous; no malignant tumors were found.
- Two cases receiving postoperative irradiation showed no recurrence.
- Recurrence occurred in a falx meningioma (NF2) and a suprasellar meningioma, with the latter experiencing severe deficits.
Implications:
- Complete tumor resection is recommended for pediatric meningiomas.
- Postoperative irradiation may be beneficial for residual tumors to minimize recurrence risk.
- These cases exhibit features intermediate between adult and pediatric meningiomas due to patient age.