Related Experiment Videos
Laparoscopic bipolar coagulation for the conservative treatment of adenomyomata
D R Phillips1, H G Nathanson, S J Milim
1Department of Obstetrics and Gynecology, South Nassau Communities Hospital, Oceanside, New York, USA.
Study Objective:
To assess the effectiveness of treating adenomyomata with laparoscopic bipolar coagulation.
Design:
Prospective, observational study. Setting. The gynecology department of a community hospital.
Patients:
Ten women, each with severe dysmenorrhea, chronic menorrhagia, and adenomyomata diagnosed by magnetic resonance imaging.
Interventions:
Laparoscopic bipolar coagulation of adenomyomata.
Measurements And Main Results:
The mean (+/- SEM) total adenomyoma volume before leuprolide acetate administration was 119 +/- 16 cm3 (range 6-190 cm3); after 3 months of therapy this was reduced to 86 +/- 8 cm3 (range 6-162 cm3, p <0. 0001) a 27.7% reduction. Further reduction occurred 7 to 12 months postoperatively to 31 +/- 3.4 cm3 (range 3-155 cm3, p <0.0001), a 73.9% reduction from baseline. Twelve months postoperatively, seven (70.0%, p <0.05) women had continued resolution or significant reduction of dysmenorrhea and resolution of menorrhagia. One woman (10.0%) with unresolved dysmenorrhea and menorrhagia required hysterectomy, and two (20.0%) with recurrent menorrhagia required resection of the endomyometrium; one continued to have menorrhagia but refused further surgical or medical treatment.
Conclusions:
Conservative treatment obviated the need for major surgery in 90% of women with adenomyomata, but further evaluation of this technique is necessary to determine its definitive role.