Management of nonepidermoid cancer of the larynx

Nonepidermoid cancer of the larynx represents an extremely diverse group of diseases with differing prognoses and rationales of management. With the lack of specificity in symptoms and physical findings, proper and expeditious lesion characterization is therefore dependent on a high index of suspicion by the clinician and accurate consulting histopathology. These neoplasms can be grouped according to cells with secretory, connective tissue, lymphoreticular, or metastatic origins. Based upon this framework, this article discusses the unique aspects of these various diseases that can lead to their diagnosis, along with consideration of management options and prognostic variables.