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Diabetic scleredema: a case report and biochemical analysis for glycosaminoglycans
T Kobayashi1, Y Yamasaki, T Watanabe
1Division of Dermatology, Tokyo Daini National Hospital, Higashigaoka, Meguro, Japan.
The Journal of Dermatology
|February 1, 1997
Abstract:
We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid.