Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Meta-analysis and endocrinology

D B Petitti1

  • 1Department of Research and Evaluation, Kaiser Permanente, Southern California Region, Pasadena, California, USA.

Endocrinology and Metabolism Clinics of North America
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mortality following development of breast cancer while using oestrogen or oestrogen plus progestin: a computer record-linkage study.

British journal of cancer·2005
Same author

Approaches to heterogeneity in meta-analysis.

Statistics in medicine·2001
Same author

Rehospitalisation for neonatal jaundice: risk factors and outcomes.

Paediatric and perinatal epidemiology·2001
Same author

Emergency contraception: knowledge and attitudes of health care providers in a health maintenance organization.

Women's health issues : official publication of the Jacobs Institute of Women's Health·2001
Same author

Salt and blood pressure. Conventional wisdom reconsidered.

Evaluation review·2001
Same author

Dietary sodium and blood pressure.

The New England journal of medicine·2001
Same journal

Navigating Adrenal Disease: A Comprehensive, Practical Guide for the Clinician.

Endocrinology and metabolism clinics of North America·2026
Same journal

Adrenal Disorders in Pregnancy.

Endocrinology and metabolism clinics of North America·2026
Same journal

Diagnosis and Management of Adrenocortical Carcinoma.

Endocrinology and metabolism clinics of North America·2026
Same journal

Pheochromocytomas and Paragangliomas.

Endocrinology and metabolism clinics of North America·2026
Same journal

Hereditary Conditions Associated with Adrenocortical Carcinoma, Pheochromocytoma, and Other Adrenal Tumors: Genetic Testing and Management Recommendations.

Endocrinology and metabolism clinics of North America·2026
Same journal

Primary Bilateral Macronodular Adrenal Hyperplasia.

Endocrinology and metabolism clinics of North America·2026
See all related articles

Meta-analysis in endocrinology offers systematic research review but can oversimplify findings and ignore study variations. Critical reading is essential, as meta-analysis should complement, not replace, primary study evaluation.

Area of Science:

  • Endocrinology
  • Medical Research Methodology

Background:

  • Meta-analysis is increasingly used in endocrinology.
  • It systematically ascertains and evaluates research for drawing conclusions.

Purpose of the Study:

  • To discuss the strengths and weaknesses of meta-analysis in endocrinology.
  • To guide researchers and readers on the appropriate interpretation and use of meta-analyses.

Main Methods:

  • The abstract reviews common practices and potential pitfalls in conducting and interpreting meta-analyses.
  • It emphasizes the importance of systematic review and explicit criteria for study inclusion/exclusion.

Main Results:

  • Strengths include systematic research ascertainment and clear study selection criteria.

Related Experiment Videos

  • Weaknesses involve focusing on single effect estimates and ignoring heterogeneity, and the inability to correct for primary study bias.

    • Conclusions:

    • Performing a good meta-analysis is challenging.
    • Readers should critically evaluate meta-analyses and not let them substitute for reading primary studies or discourage original research.