Enzymes and reactions at the eukaryotic DNA replication fork

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.

Oncogene·2008

The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency.

Virology·2006

Redefining neuroprotective gene therapeutic strategies: Lessons learned from caloric restriction and NAD(+) metabolism.

Journal of Alzheimer's disease : JAD·2005

Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair.

The Journal of biological chemistry·2001

Mutation of the methylated tRNA(Lys)(3) residue A58 disrupts reverse transcription and inhibits replication of human immunodeficiency virus type 1.

Journal of virology·2001

Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists.

Molecular and cellular endocrinology·2001

Conditional dependency of oncogenic KRAS in driving ketone body catabolism and pancreatic cancer growth.

The Journal of biological chemistry·2026

Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin.

The Journal of biological chemistry·2026

Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance.

The Journal of biological chemistry·2026

Structure Determination Reveals the Mechanistic Basis of Mannose-6-P Signal Generation by the Dimeric Lysosomal Uncovering Enzyme NAGPA.

The Journal of biological chemistry·2026

The ubiquitin ligase LONRF2 inhibits glycolysis and malignant phenotypes in endometrial cancer through aldolase A degradation.

The Journal of biological chemistry·2026

The structure of the SufBC<sub>2</sub>D-SufE complex reveals the mechanism of sulfur transfer in bacterial Fe-S cluster assembly.

The Journal of biological chemistry·2026

A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad.

Nature communications·2026

Structural and biochemical analyses of a novel bacterial dual specificity phosphatase from Candidatus Chlorohelix allophototropha.

Journal of microbiology (Seoul, Korea)·2026

Enzyme-Activatable Fluorogenic Probes: Design Strategies, Biomedical Applications, and Future Perspectives.

Journal of the American Chemical Society·2026

Multimolecular proofreading overcomes the activity-fidelity trade-off.

Cell systems·2026

Engineering Organelle-Gated Reporters for Imaging Subcellular Enzyme Activity in Living Cells.

Journal of the American Chemical Society·2026

Photochemistry of CryB from Rhodobacter sphaeroides.

Photochemistry and photobiology·2026

Related Experiment Videos

Enzymes and reactions at the eukaryotic DNA replication fork

Related Concept Videos

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.

The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency.

Redefining neuroprotective gene therapeutic strategies: Lessons learned from caloric restriction and NAD(+) metabolism.

Regulatory roles of p21 and apurinic/apyrimidinic endonuclease 1 in base excision repair.

Mutation of the methylated tRNA(Lys)(3) residue A58 disrupts reverse transcription and inhibits replication of human immunodeficiency virus type 1.

Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists.

Conditional dependency of oncogenic KRAS in driving ketone body catabolism and pancreatic cancer growth.

Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin.

Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance.

Structure Determination Reveals the Mechanistic Basis of Mannose-6-P Signal Generation by the Dimeric Lysosomal Uncovering Enzyme NAGPA.

The ubiquitin ligase LONRF2 inhibits glycolysis and malignant phenotypes in endometrial cancer through aldolase A degradation.

The structure of the SufBC<sub>2</sub>D-SufE complex reveals the mechanism of sulfur transfer in bacterial Fe-S cluster assembly.

A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad.

Structural and biochemical analyses of a novel bacterial dual specificity phosphatase from Candidatus Chlorohelix allophototropha.

Enzyme-Activatable Fluorogenic Probes: Design Strategies, Biomedical Applications, and Future Perspectives.

Multimolecular proofreading overcomes the activity-fidelity trade-off.

Engineering Organelle-Gated Reporters for Imaging Subcellular Enzyme Activity in Living Cells.

Photochemistry of CryB from Rhodobacter sphaeroides.

Related Experiment Videos

Enzymes and reactions at the eukaryotic DNA replication fork

Related Concept Videos

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