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Arthritis with sigmoid volvulus and HL-A B27
Rheumatology and Rehabilitation
|August 1, 1977
Summary
A patient experienced joint pain and digestive issues, which were resolved after surgery for a bowel condition. This case highlights the link between gastrointestinal problems and inflammatory arthritis.
Area of Science:
- Gastroenterology
- Rheumatology
- Genetics
Background:
- Chronic gastrointestinal symptoms including abdominal pain, distension, and constipation preceded the onset of arthritis.
- The patient presented with seronegative polyarthritis following a brief episode of diarrhea.
Observation:
- Surgical exploration revealed a chronic sigmoid volvulus.
- Sigmoid colectomy was performed to address the bowel obstruction.
Findings:
- Post-surgery, the patient experienced complete resolution of gastrointestinal symptoms and arthritis.
- Radiological assessment indicated improvement in affected joints.
- Human Leukocyte Antigen B27 (HLA-B27) antigen was detected in tissue typing.
Implications:
- This case suggests a potential association between chronic sigmoid volvulus and seronegative polyarthritis.
- Resolution of bowel pathology led to remission of arthritis, supporting a link.
- The presence of HLA-B27 warrants further investigation into its role in this patient's presentation.