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A Thin-skull Window Technique for Chronic Two-photon In vivo Imaging of Murine Microglia in Models of Neuroinflammation
Published on: September 19, 2010
Neurosyphilis in patients with AIDS
D E Harris1, D S Enterline, R D Tien
1Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Neuroimaging Clinics of North America
|May 1, 1997
Summary
Neurosyphilis is increasingly prevalent in immunocompromised individuals, particularly those with acquired immunodeficiency syndrome (AIDS). Recognizing its neurologic symptoms and neuroimaging findings is crucial for timely diagnosis in this population.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Syphilis prevalence is rising, especially among immunocompromised individuals.
- Acquired immunodeficiency syndrome (AIDS) is a primary driver of increased immunocompromised populations.
- Neurosyphilis, a manifestation of syphilis affecting the nervous system, requires increased clinical awareness.
Purpose of the Study:
- To reintroduce clinicians to neurosyphilis.
- To highlight the neurologic symptoms and neuroimaging characteristics of neurosyphilis.
- To emphasize the importance of considering neurosyphilis in patients with AIDS.
Main Methods:
- Review of clinical presentations of neurosyphilis.
- Analysis of neuroimaging findings in neurosyphilis.
- Correlation of symptoms and imaging with diagnosis.
Main Results:
- Neurosyphilis presents with diverse neurologic symptoms.
- Specific neuroimaging findings are characteristic of neurosyphilis.
- Early recognition is vital for effective management.
Conclusions:
- Increased prevalence of syphilis, particularly neurosyphilis, is linked to the rise in immunocompromised patients, notably those with AIDS.
- Familiarity with neurosyphilis's neurologic symptomatology and neuroimaging is essential for diagnosis.
- Clinicians should consider neurosyphilis in immunocompromised patients presenting with relevant symptoms or imaging findings.
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