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[Leukotriene antagonists. A new therapeutic approach in asthma]
P Chanez1, Y H Bougeard, I Vachier
1Clinique des Maladies respiratoires, Hôpital Arnaud de Villeneuve, Montpellier. PChanez.asmanet@Parisnet
Abstract:
BRONCHIAL INFLAMMATION: Corticosteroids are currently the most important treatment for bronchial inflammation in asthma. SULFIDOPEPTIDE LEUKOTRIENES: These biologically active fatty acids play an important role in the inflammation process in asthma. A NEW THERAPEUTIC APPROACH: Some leukotriene receptor antagonists and synthesis inhibitors are effective and safe treatment for mild to moderate asthma. GLOBAL STRATEGY: The role of these new drugs in the management of asthma remains to be defined on the basis of comparative clinical trials with the standard reliever treatment: inhaled corticosteroids.