Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitiligo

C Le Poole1, R E Boissy

  • 1Department of Dermatology, University of Cincinnati, OH 45267-0592, USA.

Seminars in Cutaneous Medicine and Surgery
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

Vitiligo causes progressive melanocyte loss, leading to depigmentation. Various treatments exist, including phototherapy and skin grafting, indicating it is not an untreatable condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Morphological and transcriptional evaluation of multiple facial cutaneous hyperpigmented spots.

Skin health and disease·2022
Same author

Vitiligo: current medical and scientific understanding.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia·2011
Same author

Mechanism of tyrosinase inhibition by deoxyArbutin and its second-generation derivatives.

The British journal of dermatology·2008
Same author

Gene transfer in human skin with different pseudotyped HIV-based vectors.

Gene therapy·2007
Same author

The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour.

The British journal of dermatology·2003
Same author

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.

The British journal of dermatology·2002
Same journal

Systemic therapy for advanced cutaneous squamous cell carcinoma.

Seminars in cutaneous medicine and surgery·2019
Same journal

Atypical Fibroxanthoma.

Seminars in cutaneous medicine and surgery·2019
Same journal

Introduction, High-Risk Skin Cancer.

Seminars in cutaneous medicine and surgery·2019
Same journal

Emerging technologies for health information in dermatology: opportunities and drawbacks of web-based searches, social media, mobile applications, and direct-to-consumer genetic testing in patient care.

Seminars in cutaneous medicine and surgery·2019
Same journal

MoleMapper: an application for crowdsourcing mole images to advance melanoma early-detection research.

Seminars in cutaneous medicine and surgery·2019
Same journal

Digital imaging applications and informatics in dermatology.

Seminars in cutaneous medicine and surgery·2019
See all related articles

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Vitiligo is a progressive depigmentation disorder caused by melanocyte loss.
  • Clinical subtypes suggest diverse etiologies.
  • Distinguishing vitiligo from other hypopigmentation disorders is crucial for treatment selection.

Purpose of the Study:

  • To review the causes, diagnosis, and treatment of vitiligo.
  • To highlight the importance of differentiating vitiligo from other conditions.
  • To emphasize that vitiligo is a treatable disorder.

Main Methods:

  • Review of existing literature on vitiligo.
  • Analysis of clinical presentations and diagnostic criteria.
  • Summary of current and emerging therapeutic strategies.

Related Experiment Videos

Main Results:

  • Vitiligo pathogenesis may involve genetic predisposition and environmental triggers.
  • Abnormalities in melanocytes increase vulnerability to external factors.
  • Effective treatments include phototherapy, corticosteroids, and cell transplantation.

Conclusions:

  • Vitiligo is a complex disorder with multiple contributing factors.
  • Accurate diagnosis is essential for effective management.
  • A range of treatments can improve cosmetic outcomes and patient quality of life, challenging the notion of vitiligo being untreatable.