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Cloning and characterization of the cDNA encoding mouse dipeptidyl peptidase I (cathepsin C)
M J McGuire1, P E Lipsky, D L Thiele
1Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas 75235-8577, USA. mjmcguir@ix.netcom.com
Biochimica Et Biophysica Acta
|April 10, 1997
Abstract:
The mouse dipeptidyl peptidase I cDNA has been cloned and sequenced and patterns of DPPI mRNA expression in various tissues characterized. Sequences encoding DPPI are highly conserved among mouse, rat and human and include an unusually long propeptide and a distinctive tyrosine adjacent to the active site cysteine.