Unilateral nevoid telangiectasia: occurrence in two patients with hepatitis C

Unilateral nevoid telangiectasia, a rarely reported disorder, has been said to be related to increased estrogen receptors in involved skin. The lesions may be congenital or acquired. When acquired it arises almost exclusively during periods of relatively increased estrogen levels such as during pregnancy or puberty, or in association with alcoholic cirrhosis. We describe unilateral nevoid telangiectasia in two young men without any evidence of cirrhosis, but with serologic evidence of hepatitis C infection. Tissue specimens from these men were analyzed for estrogen and progesterone receptors, but there was no difference in involved versus uninvolved skin.