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Aortic stenosis in children: 19-year experience
1Department of Pediatrics, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Summary
This study investigated aortic stenosis (AS) in Chinese children, finding unique features compared to Western populations. Open-heart surgery proved effective and safe for treating pediatric aortic stenosis.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Aortic Stenosis
Background:
- Limited Taiwanese literature exists on aortic stenosis (AS) features.
- This study focuses on the characteristics of AS in Chinese pediatric patients.
Purpose of the Study:
- To explore and describe the clinical, electrocardiographic, echocardiographic, and catheterization findings of aortic stenosis in Chinese children.
- To review treatment methods and outcomes for pediatric aortic stenosis.
Main Methods:
- Retrospective review of 51 children with AS out of 3808 undergoing cardiac catheterization over 19 years.
- Analysis of clinical data, diagnostic findings, treatment strategies, and patient outcomes.
Main Results:
- Valvular AS was most common (76.5%), followed by supravalvular (13.7%) and subvalvular (9.8%).
- Associated cardiovascular defects, particularly aortic regurgitation, were frequent (84.3%).
- Open-heart surgery demonstrated effective pressure gradient reduction and safety, while balloon dilation efficacy requires further study.
Conclusions:
- Pediatric AS in Chinese children exhibits distinct features compared to Western cohorts, including lower incidence and different subtype prevalence.
- Associated anomalies like Williams syndrome were more common, and isolated AS less frequent.
- Open-heart surgery is a safe and effective treatment for pediatric aortic stenosis, though balloon valvuloplasty's role needs further evaluation.