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Lignocaine aerosol spray in outpatient hysteroscopy: a randomized double-blind placebo-controlled trial
A Davies1, R E Richardson, H O'Connor
1Minimally Invasive Therapy Unit, Royal Free Hospital, London, United Kingdom.
Objective:
To assess the efficacy of lignocaine spray during outpatient hysteroscopy in reducing the need for additional anesthesia and reducing the discomfort of the procedure.
Design:
A randomized double-blind, placebo-controlled trial.
Setting:
An undergraduate university teaching hospital in London.
Patient(S):
One hundred twenty patients undergoing outpatient hysteroscopy.
Intervention(S):
Application of lignocaine spray to the cervix, cervical canal, and uterine cavity during outpatient hysteroscopy.
Main Outcome Measure(S):
The need to use additional anesthesia and the pain experienced at various steps of the procedure.
Result(S):
Women treated with active spray experienced significantly less pain when the cervix was grasped with a tenaculum at the start of hysteroscopy. There were no other significant differences in the outcome of hysteroscopy between the placebo and lignocaine groups, although there was a significant reduction in the use of additional anesthesia in both groups compared with historical controls.
Conclusion(S):
Lignocaine spray has beneficial effects on cervical but not uterine sensation. Pretreatment with either lignocaine or placebo seems to reduce the need for additional intracervical anesthesia during hysteroscopy.