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Updated: Oct 20, 2026

In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
Published on: July 27, 2010
Importance of the neural predilection of Mycobacterium leprae in leprosy
Abstract:
It is suggested that continuous leakage of bacilli into the circulation from a primary focus of intraneural infection may simultaneously initiate bacillary dissemination and the suppression of cell-mediated immunity. Both these features are essential for the development of lepromatous leprosy. Nerve involvement in leprosy, previously thought of as a diagnostic feature of the disease and as a complication of therapy, may represent an essential phase in the cycle of infection and reinfection by Mycobacterium leprae.
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