Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mood disorders and menopause

T Pearlstein1, K Rosen, A B Stone

  • 1Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island, USA.

Endocrinology and Metabolism Clinics of North America
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response of spring wheat and potato to foliar application of Zn, Mn and EDTA fertilizers on <sup>137</sup>Cs uptake.

Journal of environmental radioactivity·2020
Same author

Transfer of radionuclides and dose assessment to ants and anthills in a Swedish forest ecosystem.

Journal of environmental radioactivity·2018
Same author

Response to omalizumab using patient enrichment criteria from trials of novel biologics in asthma.

Allergy·2017
Same author

Rapid gamma spectrometric analysis of soil samples after radioactive fallout using a "conjugate view" technique.

Journal of environmental radioactivity·2017
Same author

Treatment of advanced canine anal sac adenocarcinoma with hypofractionated radiation therapy: 77 cases (1999-2013).

Veterinary and comparative oncology·2016
Same author

Interception and transfer of wet-deposited (134)Cs to potato foliage and tubers.

Journal of environmental radioactivity·2015
Same journal

Navigating Adrenal Disease: A Comprehensive, Practical Guide for the Clinician.

Endocrinology and metabolism clinics of North America·2026
Same journal

Adrenal Disorders in Pregnancy.

Endocrinology and metabolism clinics of North America·2026
Same journal

Diagnosis and Management of Adrenocortical Carcinoma.

Endocrinology and metabolism clinics of North America·2026
Same journal

Pheochromocytomas and Paragangliomas.

Endocrinology and metabolism clinics of North America·2026
Same journal

Hereditary Conditions Associated with Adrenocortical Carcinoma, Pheochromocytoma, and Other Adrenal Tumors: Genetic Testing and Management Recommendations.

Endocrinology and metabolism clinics of North America·2026
Same journal

Primary Bilateral Macronodular Adrenal Hyperplasia.

Endocrinology and metabolism clinics of North America·2026
See all related articles

Menopause does not increase depression rates, though mood changes may precede it. Hormone replacement therapy (HRT) may help some menopausal mood symptoms, but further research is needed.

Area of Science:

  • Reproductive endocrinology
  • Menopause studies
  • Psychiatry

Background:

  • Menopause is not directly linked to increased depression rates.
  • Mild mood and anxiety symptoms can occur pre-menopause.
  • Women with prior mood disorders are at higher risk during menopause.

Purpose of the Study:

  • To investigate the efficacy of hormone replacement therapy (HRT) for mood enhancement in menopausal women.
  • To evaluate the role of estrogen, progesterone, and androgens in menopausal psychological symptoms.
  • To provide guidance on managing psychological symptoms during menopause.

Main Methods:

  • Review of existing studies on menopause and depressive symptoms.
  • Analysis of research on the psychological effects of hormone therapy (estrogen, progesterone, androgens).

Related Experiment Videos

  • Comparison of HRT and psychotropic medication for menopausal mood disturbances.

    • Main Results:

    • Estrogen may have mood-elevating properties, but evidence requires further systematic study.
    • HRT may be a viable first-line treatment for minor psychological symptoms or those with vasomotor symptoms.
    • Antidepressant medication is recommended for severe or unresponsive psychological symptoms.

    Conclusions:

    • Menopause itself is not a cause of depression, but risk factors exist.
    • HRT's psychological benefits need more rigorous investigation.
    • Treatment decisions for menopausal mood symptoms should consider symptom severity and response to HRT.