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[Morphine metabolism--pharmacokinetics and pharmacodynamics]
G Andersen1, L L Christrup, P Sjøgren
1Amtssygehuset i Herlev, smerteklinikken, anaestesiologisk afdeling, Farmaceutisk Højskole, København.
Ugeskrift for Laeger
|May 26, 1997
Summary
Morphine metabolites morphine-3-glucuronide (M-3-G) and morphine-6-glucuronide (M-6-G) have complex clinical effects. M-6-G offers analgesia, while M-3-G may cause adverse reactions, especially in renal insufficiency.
Area of Science:
- Pharmacology
- Clinical Chemistry