[Cellular immunity in mice immunized with pertussis vaccine]

The authors studied the developmental mechanism of postvaccinal resistanceof mice (C57BL/6J and CC57Br) to the intracerebral infection with the virulent B. pertussis culture. A model of syngenous transfer of various cells of the immunized donors (peritoneal cells, cells of neuroglia, the spleen, thymus and the lymph nodes) was used. Marked adoptive immunity proved to originate in the use of peritoneal cells which provided protection of 57--100% of the recipients. Preliminary inactivation of the vaccine by heating was accompanied by the loss of the cell capacity of the immunized donors to cause adoptive immunity in the recipients.