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[The study of correlation between hemorrheology and fluorescein angiography in open-angle glaucoma]
1Zhongshan Ophthalinic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
Purpose:
To observe the correlation between hemorrheology and arm-retinal filling time of fluorescein angiogaphy in patients with primary open-angle glaucoma.
Methods:
The whole blood apparent viscosity in high (125 S-1), moderate (23 S-1) and low (1.2435 S-1) shear rates, plasma viscosity and hematocrit were measured in 50 cases (50 eyes) with primary open-angle glaucoma whose intraocular pressures were controlled. They also underwent fluorescein angiography. The duration from arm to retina arteria filling was named arm-retinal arteria filling time.
Results:
There were positive correlation between the whole blood apparent viscosity in high and moderate shear rates, hematocrit and arm-retinal arteria filling time (P < 0.05-0.005). The higher blood viscosity, the longer arm-retinal arteria filling time.
Conclusion:
The blood viscosity in patients with primary open-angle glaucoma can affect the arm-retinal arteria filling time of fluorescein angiography. So, the increasing blood viscosity in patients with primary open-angle glaucoma can reduce the blood supply to the optic disc.