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Updated: Aug 12, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Prognostic factors in malignant melanoma
M Kashani-Sabet1, S P Leong, R Sagebiel
1Department of Dermatology, University of California, San Francisco, Mount Zion Medical Center, San Francisco, California 94143, USA.
Abstract:
The clinical spectrum and biologic behavior of melanoma are heterogeneous. Several clinical factors may include sex, location, and age. Histologic prognostic factors may include tumor type, tumor thickness, and mitotic index in relationship to the primary tumor. With respect to metastatic melanoma, the prognostic factors may include lymph node status, number of lymph nodes, and extracapsular extension. Cytogenetic and molecular determinants of progression of melanoma may aid the current prognostic factors when they are established more firmly. Current surgical treatment is determined by the clinical and histologic factors.
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