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Serological evidence for active Epstein-Barr virus infection in multifocal choroiditis
P S Bhende1, J Biswas, H N Madhavan
1Vision Research Foundation, Medical Research Foundation Sankara Nethralaya, Madras.
Indian Journal of Pathology & Microbiology
|April 1, 1997
Abstract:
Six patients, consisting of 4 males and 2 females with mean average age fo 29.20 years, with variable picture of multifocal choroiditis were serologically investigated for their association with Epstein-Barr Virus (EBV) infection. IgG and IgM antibodies to EBV-Virus Capsid Antigen (VCA) were assayed by immunoperoxidase method on EBV infected lymphoblast cells (P3HR-1 Burkitt's lymphoma cell line). In these patients definite serological evidence of EBV infection with high titres of IgG and IgM antibodies to EBV-VCA was demonstrated suggestive of active continuing or persisting EBV infection.